Bone Marrow Aspirate Concentrate
Cellular concentrate derived from iliac crest marrow — applied in cartilage, ligament, and tendon procedures where higher concentrations of regenerative signaling cells are clinically indicated.
What It Is / How It Works
Bone Marrow Aspirate Concentrate (BMAC) is harvested from the posterior iliac crest — a minimally invasive procedure performed under local anesthesia. The aspirate is then centrifuged to concentrate mesenchymal stem cells (MSCs), hematopoietic progenitor cells, platelets, and a broad array of growth factors. This multi-cellular concentrate carries a more complex regenerative signal than PRP alone, making it particularly suited for cartilage and higher-demand tissue applications.
MSCs within BMAC have the capacity to differentiate into cartilage, bone, and connective tissue lineages. They also exert paracrine effects — modulating the local inflammatory environment and promoting endogenous healing through cell signaling rather than direct cell replacement.
Who Is a Candidate
What to Expect
Evidence Base
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