Adipose-Derived Cellular Therapy
Stromal vascular fraction harvested from adipose tissue via minimally invasive technique — used in degenerative joint applications where a concentrated cellular environment supports tissue repair.
What It Is / How It Works
Adipose-Derived Cellular Therapy utilizes the stromal vascular fraction (SVF) — a heterogeneous population of cells obtained from fat tissue harvested via a small-volume lipoaspirate. SVF contains adipose-derived mesenchymal stem cells (AD-MSCs), endothelial progenitor cells, macrophages, pericytes, and a rich cytokine milieu. Adipose tissue is an abundant source of regenerative cells, typically yielding higher cell concentrations than bone marrow per volume harvested.
The harvested fat is processed using mechanical or enzymatic digestion to release the SVF, which is then delivered via ultrasound-guided injection to the target joint or tissue. The mechanism of action is primarily paracrine — SVF cells secrete anti-inflammatory cytokines, pro-angiogenic factors, and immunomodulatory signals that create a permissive environment for tissue repair.
Who Is a Candidate
What to Expect
Evidence Base
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